PHENYLALANINE: Uses, Side Effects, Interactions and Warnings. References: Beckmann, H., Strauss, M. Dl- phenylalanine in depressed patients: an open study. Beelen, M., Tieland, M., Gijsen, A. P., Vandereyt, H., Kies, A. K., Kuipers, H., Saris, W. H., Koopman, R., and van Loon, L. Coingestion of carbohydrate and protein hydrolysate stimulates muscle protein synthesis during exercise in young men, with no further increase during subsequent overnight recovery. J Nutr 2. 00. 8; 1. M., Binnert, C., Chiolero, R. L., Taylor, W., Raffoul, W., Cayeux, M. C., Benathan, M., Shenkin, A., and Tappy, L. Trace element supplementation after major burns increases burned skin trace element concentrations and modulates local protein metabolism but not whole- body substrate metabolism. Am J Clin Nutr 2. Boirie, Y., Albright, R., Bigelow, M., and Nair, K. Impairment of phenylalanine conversion to tyrosine in end- stage renal disease causing tyrosine deficiency. Kidney Int 2. 00. A., Yang, Y., Moore, D. Greater stimulation of myofibrillar protein synthesis with ingestion of whey protein isolate v. Br. J Nutr 9- 2. 8- 2. Oral and topical L- phenylalanine, clobetasol propionate, and UVA/sunlight- -a new study for the treatment of vitiligo. J Drugs Dermatol 2. Treatment of vitiligo with oral and topical phenylalanine: 6 years of experience. Phenylketonuria Definition Phenylketonuria (PKU) can be defined as a rare metabolic disorder caused by a deficiency in the production of the hepatic (liver) enzyme. Find patient medical information for DHA DOCOSAHEXAENOIC ACID on WebMD including its uses, effectiveness, side effects and safety, interactions, user ratings and. The amino acid metabolism page details the synthesis and breakdown of essential and non-essential amino acids. Phenylketonuria (PKU) — Learn about symptoms and treatment (including a PKU diet) of this rare inherited disorder. Hyperphenylalaninemia Vs Pku Diet ChildrenArch Dermatol 1. 99. Aromatic amino acids and modification of parkinsonism. N Engl. J Med 2- 1. B., Dunn, M., Gilani, G. Phenylalanine kinetics differ between formula- fed and human milk- fed preterm infants. J Nutr 2. 00. 4; 1. E., Safar, A., Schutzler, S., Memelink, R., Ferrando, A., Spencer, H., van, Helvoort A., and Wolfe, R. Muscle protein synthesis in cancer patients can be stimulated with a specially formulated medical food. Clin Nutr 2. 01. 1; 3. Leg glucose and protein metabolism during an acute bout of resistance exercise in humans. J Appl Physiol 2. Nutritional issues in treating phenylketonuria. Festi, D., Capodicasa, S., Sandri, L., Colaiocco- Ferrante, L., Staniscia, T., Vitacolonna, E., Vestito, A., Simoni, P., Mazzella, G., Portincasa, P., Roda, E., and Colecchia, A. Measurement of hepatic functional mass by means of 1. C- methacetin and 1. C- phenylalanine breath tests in chronic liver disease: comparison with Child- Pugh score and serum bile acid levels. World J Gastroenterol 1- 7- 2. Fischer, E., Heller, B., Nachon, M., and Spatz, H. Therapy of depression by phenylalanine. Arzneimittelforschung. Hjiej, H., Doyen, C., Couprie, C., Kaye, K., and Contejean, Y. Encephale 2. 00. 8; 3. Dietary Treatment of the Untreated Adult PKU. United Kingdom: The National Society for Phenylketonuria; 2. Huang, L., Hogewind- Schoonenboom, J. J., de, Groof F., Voortman, G. J., Schierbeek, H., Twisk, J. W., Vermes, A., Chen, C., Huang, Y., and van Goudoever, J. Methionine requirement of the enterally fed term infant in the first month of life in the presence of cysteine. Phenylketonuria (PKU) is a disease that's inherited that increases the levels of phenylalanine in the blood. If left untreated, high phenylalanine levels can cause. In order for the body to use protein from the food we eat, it is broken down into smaller parts called amino acids. Special enzymes then make changes. Although this term is commonly used, it is technically incorrect, since parenteral nutrition. Find patient medical information for PHENYLALANINE on WebMD including its uses, effectiveness, side effects and safety, interactions, user ratings and products that. Program Overview: The Newborn Screening Program for genetic, endocrine and metabolic disorders identifies newborn babies who may be at risk for one of several serious. Am J Clin Nutr 2. L., Paddon- Jones, D., Zhang, X. J., Aarsland, A., and Wolfe, R. Whey protein ingestion in elderly persons results in greater muscle protein accrual than ingestion of its constituent essential amino acid content. Nutr Res 2. 00. 8; 2. Koch, R., Hanley, W., Levy, H., Matalon, K., Matalon, R., Rouse, B., Trefz, F., Guttler, F., Azen, C., Platt, L., Waisbren, S., Widaman, K., Ning, J., Friedman, E. G., and de la, Cruz F. The Maternal Phenylketonuria International Study: 1. Pediatrics 2. 00. Pt 2): 1. 52. 3- 1. Koopman, R., Verdijk, L. B., Beelen, M., Gorselink, M., Kruseman, A. J., Kuipers, H., and van Loon, L. Co- ingestion of leucine with protein does not further augment post- exercise muscle protein synthesis rates in elderly men. Br. J Nutr 2. 00. Dietary supplements of phenylalanine and other amino acid precursors of brain neuroamines in the treatment of depressive disorders. J Am Osteopath. Assoc 1. Suppl): 1. 19- 1. E., Guttler, F., Hanley, W. B., Matalon, R., Rouse, B., Trefz, F. K., de la, Cruz F., Azen, C. Pregnancy experiences in the woman with mild hyperphenylalaninemia. Pediatrics 2. 00. Pt 2): 1. 54. 8- 1. Mac. Donald, A., Evans, S., Cochrane, B., and Wildgoose, J. Weaning infants with phenylketonuria: a review. J., Koopman, R., Beelen, M., Gijsen, A. The muscle protein synthetic response to carbohydrate and protein ingestion is not impaired in men with longstanding type 2 diabetes. J Nutr 2. 00. 8; 1. D., Snyderman, S., and Gershon, S. D- phenylalanine in endogenous depression. Am. J. Psychiatry 1. D., Koch, R., and Nelson, M., Jr. Brain phenylalanine concentrations in phenylketonuria: research and treatment of adults. Pediatrics 2. 00. Pt 2): 1. 57. 5- 1. Okano, Y., Hase, Y., Kawajiri, M., Nishi, Y., Inui, K., Sakai, N., Tanaka, Y., Takatori, K., Kajiwara, M., and Yamano, T. In vivo studies of phenylalanine hydroxylase by phenylalanine breath test: diagnosis of tetrahydrobiopterin- responsive phenylalanine hydroxylase deficiency. Pediatr Res 2. 00. Leucine- enriched essential amino acid supplementation during moderate steady state exercise enhances postexercise muscle protein synthesis. Am J Clin Nutr 2. A., Green, A., Brown, G. Egg and breast milk based nitrogen sources compared. Arch Dis Child 1. Large neutral amino acids supplementation in phenylketonuric patients. J., Johnstone, J., and Kaplan, B. Nutrient supplementation approaches in the treatment of ADHD. C., Fawcett, J., Gusovsky, F., Javaid, J. I., Wynn, P., Edwards, J., Jeffriess, H., and Kravitz, H. Clinical studies on the phenylethylamine hypothesis of affective disorder: urine and blood phenylacetic acid and phenylalanine dietary supplements. J Clin Psychiatry 1. R., Gutlich, M., Lemke, K. R., Rodl, W., Swanson, N. N., Hitzemann, K., and Ziegler, I. Regulation of melanin biosynthesis in the human epidermis by tetrahydrobiopterin. Science 3- 1. 1- 1. Bolus arginine supplementation affects neither muscle blood flow nor muscle protein synthesis in young men at rest or after resistance exercise. J Nutr 2. 01. 1; 1. M., Francois, B., ter Horst, N. High phenylalanine levels directly affect mood and sustained attention in adults with phenylketonuria: a randomised, double- blind, placebo- controlled, crossover trial. Thompson, P., Balis, F., Serabe, B. M., Berg, S., Adamson, P., Klenke, R., Aiken, A., Packer, R., Murry, D. J., Jakacki, R., and Blaney, S. Pharmacokinetics of phenylacetate administered as a 3. Cancer Chemother. Pharmacol 2. 00. 3; 5. J., Hoeksma, M., Reijngoud, D. Large neutral amino acids in the treatment of PKU: from theory to practice. A randomised placebo controlled exploratory study of vitamin B- 1. L- phenylalanine (the . J Neurol. Neurosurg. Psychiatry 2. 00. Tyrosine supplementation for phenylketonuria. Cochrane. Database. Syst. Rev. Relation of prenatal phenylalanine exposure to infant and childhood cognitive outcomes: results from the International Maternal PKU Collaborative Study. Pediatrics 2. 00. Pt 2): 1. 53. 7- 1. Zhao, G., P6u H, and Fan, M. Zhonghua Yi. Xue. Za Zhi. View abstract. Antoniou C, Schulpis H, Michas T, et al. View abstract. Baker GB, Bornstein RA, Rouget AC, et al. Biol Psychiatry 1. View abstract. Baruzzi A, Contin M, Riva R, et al. Influence of meal ingestion time on pharmacokinetics of orally administered levodopa in parkinsonian patients. Clin Neuropharmacol 1. View abstract. Beckmann H, Athen D, Olteanu M, Zimmer R. DL- phenylalanine versus imipramine: a double- blind controlled study. Arch Psychiatr Nervenkr 1. View abstract. Birkmayer W, Riederer P, Linauer W, Knoll J. L- deprenyl plus L- phenylalanine in the treatment of depression. J Neural Transm 1. View abstract. Bornstein RA, Baker GB, Carroll A, et al. Psychiatry Res 1. View abstract. Cederbaum S. Phenylketonuria: an update. Curr Opin Pediatr 2. View abstract. Cejudo- Ferragud, E., Nacher, A., Polache, A., Cercos- Fortea, T., Merino, M., and Casabo, V. Evidence of competitive inhibition for the intestinal absorption of baclofen by phenylalanine. Int J of Pharm (Amsterdam) 1. Cormane RH, Siddiqui AH, Westerhof W, Schutgens RB. Arch Dermatol Res 1. View abstract. Cotzias GC, Van Woert MH, Schiffer LM. Aromatic amino acids and modification of parkinsonism. N Engl J Med 1. 96. Eriksson T, Granerus AK, Linde A, et al. Neurology 1. 98. 8; 3. View abstract. Food and Nutrition Board, Institute of Medicine. Washington, DC: National Academy Press, 2. Available at: http: //www. Gardos G, Cole JO, Matthews JD, et al. View abstract. Heller B, Fischer BE, Martin R. Therapeutic action of D- phenylalanine in Parkinson's disease. Arzneimittelforschung 1. View abstract. Jardim LB, Palma- Dias R, Silva LC, et al. Acta Paediatr 1. 99. View abstract. Jukic T, Rojc B, Boben- Bardutzky D, Hafner M, Ihan A. The use of a food supplementation with D- phenylalanine, L- glutamine and L- 5- hydroxytriptophan in the alleviation of alcohol withdrawal symptoms. Coll Antropol 2. 01. View abstract. Juncos JL, Fabbrini G, Mouradian MM, et al. Dietary influences on the antiparkinsonian response to levodopa. Arch Neurol 1. 98. View abstract. Kasa RM. View abstract. Kitade T, Odahara Y, Shinohara S, et al. Studies on the enhanced effect of acupuncture analgesia and acupuncture anesthesia by D- phenylalanine (2nd report)- schedule of administration and clinical effects in low back pain and tooth extraction. Acupunct Electrother Res 1. View abstract. Kuiters GR, et al. Oral phenylalanine loading and sunlight as source of UVA irradiation in vitiligo on the Caribbean island of Curacao NA. J Trop Med Hyg 1. View abstract. Lehmann WD, Theobald N, Fischer R, Heinrich HC. View abstract. Mitchell MJ, Daines GE, Thomas BL. View abstract. Mosnik DM, Spring B, Rogers K, Baruah S. View abstract. National Institutes of Health Consensus Development Conference Statement. Pediatrics 2. 00. View abstract. Nutt JG, Woodward WR, Hammerstad JP, et al. Relation to levodopa absorption and transport. N Engl J Med 1. 98. View abstract. PKU - Dietary Treatment of the Untreated Adult PKU. National Society for Phenylketonuria (NSPKU). Available at: web. Rouse B, Azen C, Koch R, et al. View abstract. Schulpis CH, Antoniou C, Michas T, Strarigos J.
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